Description

tert-Butyl (3S)-3-(Pyrazin-2-Ylamino)Pyrrolidine-1-Carboxylate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is of significant value for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and antiviral applications.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Peptidomimetic Synthesis: Serves as a constrained proline analog for the design and synthesis of novel peptidomimetics and macrocyclic compounds.
• API Process Development: Employed in the scale-up and process chemistry stages for the commercial manufacturing of target drug candidates.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	tert-Butyl (3S)-3-(Pyrazin-2-Ylamino)Pyrrolidine-1-Carboxylate
CAS No.	915002-35-6
Molecular Formula	C13H20N4O2
Molecular Weight	264.33 g/mol
Synonyms	1-Boc-3-[(pyrazin-2-yl)amino]-(3S)-pyrrolidine; (3S)-1-(tert-Butoxycarbonyl)-3-(pyrazin-2-ylamino)pyrrolidine; tert-Butyl (3S)-3-[(pyrazin-2-yl)amino]pyrrolidine-1-carboxylate; (S)-tert-Butyl 3-(pyrazin-2-ylamino)pyrrolidine-1-carboxylate; 1-Boc-3-(2-pyrazinylamino)-(S)-pyrrolidine; 915002-35-6; (S)-1-N-Boc-3-(pyrazin-2-ylamino)pyrrolidine
EINECS	Contact for details

Quality Control

Our tert-Butyl (3S)-3-(Pyrazin-2-Ylamino)Pyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and allowed to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.