Description

(Z)-7-[(1S,2R,3R)-3-Hydroxy-5-Oxo-2-[(E)-3-Oxooct-1-Enyl]Cyclopentyl]Hept-5-Enoic Acid is a high-purity, synthetically produced prostaglandin analog with a complex stereochemistry that is critical for its biological activity. This compound is a key advanced intermediate in the synthesis of potent pharmaceutical agents, particularly those targeting inflammatory pathways and ocular conditions. It is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and fine chemical industries who require a reliable supply of high-quality, structurally defined building blocks.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Drug Development: Used in the research and production of drugs for treating glaucoma and ocular hypertension.
• Inflammation Research: Serves as a key precursor in the development of novel anti-inflammatory agents and receptor studies.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale manufacturing of specialty therapeutics.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Applied in studies investigating prostaglandin signaling pathways and their physiological roles.

Basic Information

Product Name	(Z)-7-[(1S,2R,3R)-3-Hydroxy-5-Oxo-2-[(E)-3-Oxooct-1-Enyl]Cyclopentyl]Hept-5-Enoic Acid
CAS No.	914804-63-0
Molecular Formula	C20H30O5
Molecular Weight	350.45 g/mol
Synonyms	Prostaglandin F2α Ethanolamide Intermediate; 7-[(1S,2R,3R)-3-Hydroxy-5-oxo-2-[(1E)-3-oxo-1-octenyl]cyclopentyl]-5-heptenoic Acid; Travoprost Intermediate; Prostaglandin Analog Intermediate; 9,11,15-Trihydroxy-17-phenyl-18,19,20-trinor-prosta-5,13-dien-1-oic Acid Derivative; (5Z)-7-[(1S,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-butenyl]cyclopentyl]-5-Heptenoic Acid Related Compound; AL-8810 Related Compound; Fluprostenol Isomer
EINECS	Contact for details

Quality Control

Our (Z)-7-[(1S,2R,3R)-3-Hydroxy-5-Oxo-2-[(E)-3-Oxooct-1-Enyl]Cyclopentyl]Hept-5-Enoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for stereochemical purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing purity, impurities, and specific tests are provided and can be tailored to support regulatory filings (e.g., DMF, CMC sections).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.