Description

1-[4-Fluoro-2-(Methylsulfonyl)Phenyl]Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine carboxylic acid core and substituted phenyl ring. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas targeting central nervous system and inflammatory disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold in structure-activity relationship (SAR) studies and lead optimization for new molecular entities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Biochemical Research: Employed in the development of enzyme inhibitors or receptor modulators due to its specific chemical structure.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1-[4-Fluoro-2-(Methylsulfonyl)Phenyl]Piperidine-4-Carboxylic Acid
CAS No.	914637-73-3
Molecular Formula	C14H16FNO4S
Molecular Weight	313.35 g/mol
Synonyms	4-Fluoro-2-(methylsulfonyl)phenylpiperidine-4-carboxylic acid; 4-Piperidinecarboxylic acid, 1-[4-fluoro-2-(methylsulfonyl)phenyl]-; 1-(4-Fluoro-2-methanesulfonylphenyl)piperidine-4-carboxylic acid; 914637-73-3; UNII-9V8H2C6Y2H; 9V8H2C6Y2H; AKOS025244064; 1-(4-Fluoro-2-methylsulfonylphenyl)piperidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[4-Fluoro-2-(Methylsulfonyl)Phenyl]Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.