Description

1-[4-Fluoro-2-(Methylsulfonyl)Phenyl]Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug molecules, especially those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• API Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring a fluorinated phenylpiperidine core.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the fluorine and methylsulfonyl groups can contribute to biological activity and metabolic stability.
• Chemical Biology Probe: Employed in academic and industrial research to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up services.

Basic Information

Product Name	1-[4-Fluoro-2-(Methylsulfonyl)Phenyl]Piperidine-3-Carboxylic Acid
CAS No.	914637-71-1
Molecular Formula	C13H16FNO4S
Molecular Weight	301.34 g/mol
Synonyms	1-(4-Fluoro-2-methanesulfonylphenyl)piperidine-3-carboxylic acid; 3-Piperidinecarboxylic acid, 1-[4-fluoro-2-(methylsulfonyl)phenyl]-; 914637-71-1; 1-[4-Fluoro-2-(Methylsulfonyl)phenyl]-3-piperidinecarboxylic Acid; 1-(4-Fluoro-2-methylsulfonylphenyl)piperidine-3-carboxylic acid; 1-(4-Fluoro-2-mesylphenyl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[4-Fluoro-2-(Methylsulfonyl)Phenyl]Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.