Description

1-[2-Fluoro-4-(Methylsulfonyl)Phenyl]Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct fluorinated and sulfonated aromatic piperidine structure. This compound is of significant commercial value for its role in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, including potential central nervous system (CNS) drugs and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize lead compounds, particularly those targeting neurological pathways.
• Active Pharmaceutical Ingredient (API) Development: Serves as a critical precursor in the multi-step synthesis of potential candidate drugs.
• Biochemical Tool Compound: Employed in vitro and in vivo studies to investigate specific biological mechanisms and protein interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	1-[2-Fluoro-4-(Methylsulfonyl)Phenyl]Piperidine-3-Carboxylic Acid
CAS No.	914637-67-5
Molecular Formula	C14H16FNO4S
Molecular Weight	313.35 g/mol
Synonyms	3-Piperidinecarboxylic acid, 1-[2-fluoro-4-(methylsulfonyl)phenyl]-; 1-(2-Fluoro-4-methanesulfonylphenyl)piperidine-3-carboxylic acid; 914637-67-5; 1-[2-Fluoro-4-(methylsulfonyl)phenyl]piperidine-3-carboxylic acid; 1-(2-Fluoro-4-(methylsulfonyl)phenyl)piperidine-3-carboxylic acid; 1-(2-Fluoro-4-methanesulphonylphenyl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[2-Fluoro-4-(Methylsulfonyl)Phenyl]Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.