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1-[4-Fluoro-2-(Methylsulfonyl)Phenyl]Piperidine-4-Carboxamide CAS NO 914637-65-3


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CAS No.:914637-65-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-[4-Fluoro-2-(Methylsulfonyl)Phenyl]Piperidine-4-Carboxamide is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound is valued for its unique molecular scaffold, which incorporates key functional groups for targeted biological activity. It is primarily sought after by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and oncology research programs. Its precise structure makes it a critical building block for developing potent and selective drug candidates.

Application

  • Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
  • Drug Discovery & Medicinal Chemistry: Used as a core scaffold or building block for creating compound libraries and optimizing lead molecules in preclinical studies.
  • CNS-Targeted Therapeutics: Employed in the synthesis of potential treatments for neurological disorders, leveraging the piperidine-carboxamide motif.
  • Oncology Research: Serves as a starting material for developing novel small-molecule inhibitors targeting specific cancer pathways.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
  • Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) and novel chemical reactions.

Basic Information

Product Name 1-[4-Fluoro-2-(Methylsulfonyl)Phenyl]Piperidine-4-Carboxamide
CAS No. 914637-65-3
Molecular Formula C14H17FN2O3S
Molecular Weight 312.36 g/mol
Synonyms 4-Fluoro-2-(methylsulfonyl)-N-(4-piperidinyl)benzamide; 4-Carbamoyl-1-[4-fluoro-2-(methylsulfonyl)phenyl]piperidine; 1-[4-Fluoro-2-(Methanesulfonyl)Phenyl]Piperidine-4-Carboxamide; 914637-65-3; 4-Piperidinecarboxamide, 1-[4-fluoro-2-(methylsulfonyl)phenyl]-; Benzamide, 4-fluoro-2-(methylsulfonyl)-N-4-piperidinyl-
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Quality Control

Our 1-[4-Fluoro-2-(Methylsulfonyl)Phenyl]Piperidine-4-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (IR) Conforms
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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