Description

Benzenesulfonamide, 2,3,5-Trifluoro- is a high-purity, fluorinated aromatic sulfonamide derivative serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the strategic trifluoro substitution pattern on the benzene ring, which is essential for modulating the electronic and steric properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in protease inhibitor and kinase inhibitor research.
• Agrochemical Synthesis: Building block for advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science: Precursor for functional polymers and liquid crystals, leveraging the sulfonamide group for hydrogen bonding and self-assembly.
• Chemical Research: Versatile reagent for studying structure-activity relationships (SAR) and fluorine chemistry in academic and industrial laboratories.
• Dye & Pigment Industry: Intermediate for synthesizing specialized fluorinated colorants with improved lightfastness and solubility properties.

Basic Information

Product Name	Benzenesulfonamide, 2,3,5-Trifluoro-
CAS No.	914637-01-7
Molecular Formula	C6H4F3NO2S
Molecular Weight	211.16 g/mol
Synonyms	2,3,5-Trifluorobenzenesulfonamide; 1,2,4-Trifluoro-5-sulfamoylbenzene; 2,3,5-Trifluorophenylsulfonamide; Benzenesulfonamide, 2,3,5-trifluoro-; 5-Sulfamoyl-1,2,4-trifluorobenzene; 2,3,5-Trifluoro-1-benzenesulfonamide
EINECS	Contact for details

Quality Control

Our Benzenesulfonamide, 2,3,5-Trifluoro- is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.