Description

Methyl 4-Amino-3-Bromo-5-Chlorobenzoate is a high-purity, multi-functional halogenated benzoate ester intermediate of significant importance in advanced organic synthesis. Its molecular structure, featuring distinct amino, bromo, and chloro substituents, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

This specialized intermediate serves as a critical precursor in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its halogenated aromatic core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in catalytic systems and coordination chemistry.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other functional polymers.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments due to its substituted aniline structure.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for custom chemical synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	Methyl 4-Amino-3-Bromo-5-Chlorobenzoate
CAS No.	914636-88-7
Molecular Formula	C8H7BrClNO2
Molecular Weight	264.50 g/mol
Synonyms	Methyl 4-amino-3-bromo-5-chlorobenzoate; Benzoic acid, 4-amino-3-bromo-5-chloro-, methyl ester; 4-Amino-3-bromo-5-chlorobenzoic acid methyl ester; 3-Bromo-5-chloro-4-aminobenzoic acid methyl ester; Methyl 3-bromo-5-chloro-4-aminobenzoate; CAS 914636-88-7
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Amino-3-Bromo-5-Chlorobenzoate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specification parameters are provided with each shipment. We support compliance with relevant regulatory frameworks for our customers' target markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.