Description

3-(3'-Bromo-4'-Fluorophenyl)-3-Oxopropanenitrile is a high-purity, advanced pharmaceutical intermediate characterized by its distinct bromo-fluoro substituted aromatic ketone nitrile structure. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile building block for introducing specific halogenated motifs. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and other small molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of new herbicides and pesticides, leveraging its halogenated aromatic core for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Chemical Research & Development: Employed as a versatile synthon in organic chemistry for constructing complex heterocycles and functionalized aromatics.
• Ligand and Catalyst Preparation: Utilized in the development of specialized ligands for metal-catalyzed coupling reactions.

Basic Information

Item	Details
Product Name	3-(3'-Bromo-4'-Fluorophenyl)-3-Oxopropanenitrile
CAS No.	914636-74-1
Molecular Formula	C9H5BrFNO
Molecular Weight	242.05 g/mol
Synonyms	3-(3-Bromo-4-fluorophenyl)-3-oxopropanenitrile; 3-Oxo-3-(3-bromo-4-fluorophenyl)propanenitrile; 2-(3-Bromo-4-fluorobenzoyl)acetonitrile; (3-Bromo-4-fluorophenyl)(cyanomethyl)ketone; β-Oxo-3-bromo-4-fluorobenzeneacetonitrile; 3-Bromo-4-fluorobenzoylacetonitrile; 914636-74-1
EINECS	Contact for details

Quality Control

Our 3-(3'-Bromo-4'-Fluorophenyl)-3-Oxopropanenitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.