Description

3-(2'-Chloro-4'-Fluorophenyl)-3-Oxopropanenitrile is a high-value, multi-functional chemical intermediate characterized by its unique phenyl ketone nitrile structure. This compound matters for its critical role as a versatile building block in the synthesis of complex organic molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the chloro-fluoro phenyl moiety for enhanced biological activity and environmental profile.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable tool compound for methodological studies in organic synthesis, including cyanoacetylation and subsequent heterocycle formation.

Basic Information

Product Name	3-(2'-Chloro-4'-Fluorophenyl)-3-Oxopropanenitrile
CAS No.	914636-68-3
Molecular Formula	C9H5ClFNO
Molecular Weight	197.59 g/mol
Synonyms	2-Chloro-4-fluorobenzoylacetonitrile; 3-Oxo-3-(2-chloro-4-fluorophenyl)propanenitrile; 1-(2-Chloro-4-fluorophenyl)-2-cyanoethanone; 2-Chloro-4-fluoro-β-oxobenzeneacetonitrile; (2-Chloro-4-fluorobenzoyl)acetonitrile; 3-(2-Chloro-4-fluorophenyl)-3-oxopropionitrile; β-Oxo-2-chloro-4-fluorobenzeneacetonitrile
EINECS	Contact for details

Quality Control

Our 3-(2'-Chloro-4'-Fluorophenyl)-3-Oxopropanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.