Description

4-Fluoro-3-(Methylsulphonyl)Benzonitrile 97% is a high-purity fluorinated aromatic nitrile derivative featuring a methylsulfonyl substituent. This compound serves as a versatile and critical pharmaceutical intermediate and agrochemical building block, enabling the synthesis of advanced molecules with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine and sulfone motifs for enhanced efficacy.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with unique electronic properties.
• Organic Synthesis Reagent: A valuable synthon in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to its reactive cyano and fluoro groups.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in chemical manufacturing.

Basic Information

Product Name	4-Fluoro-3-(Methylsulphonyl)Benzonitrile 97%
CAS No.	914636-47-8
Molecular Formula	C8H6FNO2S
Molecular Weight	199.20 g/mol
Synonyms	3-(Methylsulfonyl)-4-fluorobenzonitrile; 4-Fluoro-3-(methylsulfonyl)benzonitrile; 4-Fluoro-3-methanesulfonylbenzonitrile; Benzonitrile, 4-fluoro-3-(methylsulfonyl)-; 914636-47-8; 4-Fluoro-3-methylsulfonylbenzonitrile; 3-Methylsulfonyl-4-fluorobenzonitrile
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Methylsulphonyl)Benzonitrile 97% is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.