Description

2-(2,2-Dimethylpropanoyl)-3-((2-Indol-3-Ylethyl)Amino)Prop-2-Enenitrile is a specialized organic compound featuring a unique molecular architecture combining indole and cyanoenamine functionalities. This structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a sophisticated building block for constructing compound libraries and exploring structure-activity relationships (SAR).
• Biochemical Probe Development: Acts as a core structure for developing enzyme inhibitors or receptor modulators in biochemical assays.
• Organic Synthesis: Employed in advanced organic reactions, leveraging its reactive cyano and amino groups for constructing heterocyclic systems.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	2-(2,2-Dimethylpropanoyl)-3-((2-Indol-3-Ylethyl)Amino)Prop-2-Enenitrile
CAS No.	914636-36-5
Molecular Formula	C20H23N3O
Molecular Weight	321.42 g/mol
Synonyms	3-[(2-Indol-3-ylethyl)amino]-2-(2,2-dimethylpropanoyl)prop-2-enenitrile; 2-(2,2-Dimethylpropanoyl)-3-[(2-(1H-indol-3-yl)ethyl)amino]acrylonitrile; 3-[(2-(1H-Indol-3-yl)ethyl)amino]-2-pivaloylacrylonitrile; 2-Pivaloyl-3-[(2-(1H-indol-3-yl)ethyl)amino]acrylonitrile; (2Z)-3-[(2-(1H-Indol-3-yl)ethyl)amino]-2-(2,2-dimethylpropanoyl)prop-2-enenitrile; 914636-36-5; Pivaloylacrylonitrile indole derivative
EINECS	Contact for details

Quality Control

Our production of 2-(2,2-Dimethylpropanoyl)-3-((2-Indol-3-Ylethyl)Amino)Prop-2-Enenitrile adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, critical for research and development applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.