Description

3-Bromo-5-(Trifluoromethoxy)Benzamide is a high-purity, multi-functional aromatic building block featuring both bromo and trifluoromethoxy substituents. This compound is valued for its role as a critical intermediate in advanced organic synthesis, enabling the introduction of specific functional groups and structural motifs. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its unique electronic properties imparted by the halogen and fluorine atoms.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination for constructing complex biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	3-Bromo-5-(Trifluoromethoxy)Benzamide
CAS No.	914636-32-1
Molecular Formula	C8H5BrF3NO2
Molecular Weight	284.03 g/mol
Synonyms	3-Bromo-5-(trifluoromethoxy)benzamide; Benzamide, 3-bromo-5-(trifluoromethoxy)-; 5-(Trifluoromethoxy)-3-bromobenzamide; 3-Bromo-5-trifluoromethoxybenzamide; 914636-32-1; 3-Br-5-OCF3-Benzamide; 3-Bromo-5-(trifluoromethoxy)benzoic acid amide
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(Trifluoromethoxy)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.