Description

2-Bromo-4-Carbamoyl-Alpha,Alpha,α-Trifluoroanisole, 4-(Aminocarbonyl)-4-Bromo-Alpha,Alpha,α-Trifluoroanisole CAS NO 914636-29-6 is a high-value, multi-functional aromatic intermediate characterized by its bromo, carbamoyl, and trifluoromethoxy substituents. This unique structure makes it a critical building block for synthesizing complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides that leverage the stability of the trifluoromethoxy group.
• Ligand and Catalyst Development: Used in organic and medicinal chemistry to create specialized ligands for catalysis or as a core structure in drug discovery libraries.
• Material Science Research: Potential monomer or additive for developing specialty polymers with unique electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise halogenated trifluoroanisole derivative.

Basic Information

Item	Details
Product Name	2-Bromo-4-Carbamoyl-Alpha,Alpha,α-Trifluoroanisole, 4-(Aminocarbonyl)-4-Bromo-Alpha,Alpha,α-Trifluoroanisole
CAS No.	914636-29-6
Molecular Formula	C9H5BrF3NO2
Molecular Weight	296.04 g/mol
Synonyms	2-Bromo-4-carbamoyl-α,α,α-trifluoroanisole; 4-(Aminocarbonyl)-2-bromo-α,α,α-trifluoroanisole; 2-Bromo-α,α,α-trifluoro-4-methoxybenzamide; 4-Bromo-2-(trifluoromethoxy)benzamide; 914636-29-6; Benzamide, 2-bromo-α,α,α-trifluoro-4-methoxy-; 2-Bromo-4-methoxy-α,α,α-trifluorobenzamide
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Carbamoyl-Alpha,Alpha,α-Trifluoroanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids/bases and oxidizing agents. The compound may be hygroscopic; handle and store under inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.