Description

(3-((4-(tert-Butoxycarbonyl)Piperazin-1-Yl)Sulfonyl)Phenyl)Boronic Acid is a sophisticated bifunctional building block that combines a boronic acid moiety with a Boc-protected piperazine sulfonamide group. This compound is critical for facilitating efficient cross-coupling reactions, particularly in the synthesis of complex molecules where precise structural control is paramount. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel drug candidates and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl and heterobiaryl structures found in active pharmaceutical ingredients (APIs).
• Protease Inhibitor Development: Used in the research and synthesis of molecules targeting protease enzymes, leveraging the sulfonamide pharmacophore.
• Kinase Inhibitor Scaffolds: Serves as a versatile building block for creating focused libraries of potential kinase inhibitors in medicinal chemistry programs.
• Chemical Biology Probes: Employed in the development of tool compounds and probes for studying biological pathways and target engagement.
• Agrochemical Synthesis: Applied in the creation of novel herbicides and fungicides that require the incorporation of specific aryl and sulfonamide functionalities.
• Material Science Research: Investigated for the development of novel organic electronic materials and metal-organic frameworks (MOFs) via its reactive boronic acid group.

Basic Information

Product Name	(3-((4-(tert-Butoxycarbonyl)Piperazin-1-Yl)Sulfonyl)Phenyl)Boronic Acid
CAS No.	914610-81-4
Molecular Formula	C15H23BN2O6S
Molecular Weight	370.23 g/mol
Synonyms	3-[(4-[(1,1-Dimethylethoxy)carbonyl]-1-piperazinyl)sulfonyl]benzeneboronic acid; (3-((4-(Boc)Piperazin-1-yl)Sulfonyl)Phenyl)boronic Acid; Boc-Piperazine-4-sulfonyl-phenylboronic Acid; 3-(N-Boc-piperazine-1-sulfonyl)phenylboronic acid; [3-(4-Boc-piperazine-1-sulfonyl)phenyl]boronic acid; tert-Butyl 4-[(3-boronophenyl)sulfonyl]piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our (3-((4-(tert-Butoxycarbonyl)Piperazin-1-Yl)Sulfonyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and structural integrity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.