Description

4-{4-[Bis(4-Fluorophenyl)Methyl]Piperazinyl}Benzyl Alcohol is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine and benzyl alcohol functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and receptor-targeting therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and manufacturers of fine chemicals seeking a reliable building block for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the manufacturing process of final API molecules, especially in psychotropic and antipsychotic drug classes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for clinical trials.
• Biochemical Research: Employed as a tool compound in biochemical assays to study receptor binding and enzyme inhibition.

Basic Information

Product Name	4-{4-[Bis(4-Fluorophenyl)Methyl]Piperazinyl}Benzyl Alcohol
CAS No.	914349-62-5
Molecular Formula	C24H24F2N2O
Molecular Weight	394.46 g/mol
Synonyms	1-[(4-Fluorophenyl)(4-fluorophenyl)methyl]-4-(4-(hydroxymethyl)phenyl)piperazine; 4-[4-[Bis(4-fluorophenyl)methyl]piperazin-1-yl]benzyl alcohol; 1-[Bis(4-fluorophenyl)methyl]-4-[4-(hydroxymethyl)phenyl]piperazine; 4-(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)benzyl alcohol; 914349-62-5; 4-(4-(Bis(4-fluorophenyl)methyl)piperazinyl)benzyl alcohol
EINECS	Contact for details

Quality Control

Our 4-{4-[Bis(4-Fluorophenyl)Methyl]Piperazinyl}Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.