Description

1-(4-Hydroxymethylphenyl)Piperidine-4-Carboxylic Acid Ethyl Ester is a versatile and high-purity organic building block of significant interest in advanced chemical synthesis. Its molecular structure, featuring both a hydroxymethylphenyl group and a piperidine carboxylic ester, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists and production units in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for scale-up.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes for constructing complex heterocyclic compounds and other fine chemicals.
• Chemical Research & Development: Serves as a crucial starting material or intermediate in academic and industrial R&D for new drug discovery and process chemistry.
• Ligand and Catalyst Precursor: Potential use in the development of specialized ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(4-Hydroxymethylphenyl)Piperidine-4-Carboxylic Acid Ethyl Ester
CAS No.	914349-50-1
Molecular Formula	C16H23NO3
Molecular Weight	277.36 g/mol
Synonyms	Ethyl 1-[4-(Hydroxymethyl)phenyl]-4-piperidinecarboxylate; 4-Piperidinecarboxylic acid, 1-[4-(hydroxymethyl)phenyl]-, ethyl ester; 1-(4-Hydroxymethylphenyl)-4-piperidinecarboxylic acid ethyl ester; 1-(4-(Hydroxymethyl)phenyl)piperidine-4-carboxylic acid ethyl ester; Ethyl 1-(4-(hydroxymethyl)phenyl)piperidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our 1-(4-Hydroxymethylphenyl)Piperidine-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and cGMP intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.