Description

1-Boc-3-Hydroxymethyl-2-Methylindole is a high-purity, protected indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound is essential for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile functional groups.
• Peptidomimetic Synthesis: Serves as a scaffold for creating indole-based peptidomimetics and protease inhibitors.
• Agrochemical Development: Intermediate in the research and production of novel herbicides and plant growth regulators.
• Material Science Precursor: Potential starting material for the synthesis of organic semiconductors and advanced polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and novel compound library generation.

Basic Information

Product Name	1-Boc-3-Hydroxymethyl-2-Methylindole
CAS No.	914349-13-6
Molecular Formula	C16H21NO3
Molecular Weight	275.34 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-(hydroxymethyl)-2-methyl-1H-indole; 2-Methyl-1H-indole-3-methanol, 1-(1,1-dimethylethyl) 1,2-dicarbamate (9CI); 1-Boc-2-methyl-3-indolemethanol; tert-Butyl 3-(hydroxymethyl)-2-methyl-1H-indole-1-carboxylate; 3-Hydroxymethyl-2-methylindole-1-carboxylic acid tert-butyl ester; N-Boc-3-hydroxymethyl-2-methylindole; 1-N-Boc-3-hydroxymethyl-2-methylindole; Boc-2-Me-3-Ind-CH2OH
EINECS	Contact for details

Quality Control

Our 1-Boc-3-Hydroxymethyl-2-Methylindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.