Description

(3S)-n-[(1S)-5-Amino-1-[[(2,2-Diphenylethyl)Amino]Carbonyl]Pentyl]-2-(1,4-Dioxo-4-Phenylbutyl)-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxamide is a high-purity, non-peptidic small molecule inhibitor with a complex, multi-cyclic structure. This compound is of significant interest in pharmaceutical research and development, particularly for its role as a potent and selective inhibitor of specific proteolytic enzymes. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutics for cardiovascular, inflammatory, and oncological indications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced drug candidates targeting specific enzyme pathways.
• Protease Inhibition Research: Used as a reference standard and active compound in biochemical assays to study the mechanism and kinetics of protease enzymes.
• Lead Compound Optimization: Provides a structural scaffold for medicinal chemistry programs aimed at improving pharmacokinetic properties and therapeutic efficacy.
• In Vitro & Ex Vivo Studies: Employed in cell-based assays and tissue studies to evaluate biological activity and cellular response.
• High-Throughput Screening (HTS): Acts as a control or hit compound in screening libraries to identify new biological targets or validate screening platforms.
• Academic Research: Supports fundamental research in biochemistry, enzymology, and signal transduction at universities and government labs.

Basic Information

Product Name	(3S)-n-[(1S)-5-Amino-1-[[(2,2-Diphenylethyl)Amino]Carbonyl]Pentyl]-2-(1,4-Dioxo-4-Phenylbutyl)-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxamide
CAS No.	914291-63-7
Molecular Formula	C41H46N4O4
Molecular Weight	658.84 g/mol
Synonyms	N-[(3S)-2-[(2S)-5-Amino-1-oxo-1-[[2,2-diphenylethyl]amino]pentan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carbonyl]-4-oxo-4-phenylbutanamide; (3S)-N-[(1S)-5-Amino-1-[[(2,2-diphenylethyl)amino]carbonyl]pentyl]-2-(1,4-dioxo-4-phenylbutyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide; Non-peptidic Inhibitor; Protease Inhibitor 914291-63-7
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results from HPLC, NMR, and MS are available upon request. We adhere to a quality management system to support the needs of our clients in regulated and non-regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.