Description

4-(4-Fluorophenyl)-2-Methyl-5-Thiazolecarboxylic Acid is a high-purity, fluorinated thiazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific molecular architecture enables targeted biological activity. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of novel compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated heterocycles.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the bioactivity of the thiazole core.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or emissive layer materials in electronic displays.
• Ligand for Catalysis: Can be utilized to develop specialized ligands for transition metal catalysts in asymmetric synthesis.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reactions and creating compound libraries.
• Material Science: A potential monomer or additive for creating polymers with specific thermal or optical properties.

Basic Information

Product Name	4-(4-Fluorophenyl)-2-Methyl-5-Thiazolecarboxylic Acid
CAS No.	914287-84-6
Molecular Formula	C11H8FNO2S
Molecular Weight	237.25 g/mol
Synonyms	5-Thiazolecarboxylic acid, 4-(4-fluorophenyl)-2-methyl-; 2-Methyl-4-(4-fluorophenyl)-1,3-thiazole-5-carboxylic acid; 4-(4-Fluorophenyl)-2-methyl-1,3-thiazole-5-carboxylic acid; 4-(p-Fluorophenyl)-2-methylthiazole-5-carboxylic acid; 914287-84-6; AKOS BRN 1258; 4-(4-FLUOROPHENYL)-2-METHYLTHIAZOLE-5-CARBOXYLIC ACID
EINECS	Contact for details

Quality Control

Our 4-(4-Fluorophenyl)-2-Methyl-5-Thiazolecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.