Description

2-Bromo-4-(tert-Butoxy)-4-Oxobutanoic Acid is a high-purity synthetic intermediate characterized by its reactive bromine and protected carboxylic acid functional groups. This compound matters for its role as a versatile building block in the synthesis of complex molecules, enabling precise chemical modifications. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring bromo-substituted butanoic acid derivatives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Serves as a versatile electrophile or alkylating agent in complex multi-step organic reactions, including C-C bond formation.
• Peptide Mimetics & Conjugate Chemistry: Useful for introducing bromo-handles or tert-butyl protected carboxyl groups into peptide chains or bioconjugates for further functionalization.
• Material Science Research: Employed in the development of specialty polymers and functional materials where bromine atoms can impart specific properties like flame retardancy.
• Chemical Biology Probes: Acts as a precursor for synthesizing molecular probes and inhibitors used in biochemical and cellular studies.

Basic Information

Product Name	2-Bromo-4-(tert-Butoxy)-4-Oxobutanoic Acid
CAS No.	914224-26-3
Molecular Formula	C8H13BrO4
Molecular Weight	253.09 g/mol
Synonyms	2-Bromo-4-(tert-butoxy)-4-oxobutanoic acid; 4-(tert-Butoxy)-2-bromo-4-oxobutanoic acid; Butanoic acid, 2-bromo-4-(1,1-dimethylethoxy)-4-oxo-; 2-Bromo-4-tert-butoxy-4-oxobutanoic acid; 2-Bromo-4-oxo-4-(tert-butoxy)butanoic acid; Bromosuccinic acid tert-butyl ester (derivative); tert-Butyl 2-bromosuccinate (acid form)
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(tert-Butoxy)-4-Oxobutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.