Description

2-Bromo-5-Nitronicotinic Acid is a high-purity, versatile heterocyclic building block and key synthetic intermediate. This compound is valued for its reactive bromo and nitro substituents on the pyridine ring, enabling precise functionalization in complex organic syntheses. It is primarily sought after by research chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active molecules and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	2-Bromo-5-Nitronicotinic Acid
CAS No.	914222-92-7
Molecular Formula	C6H3BrN2O4
Molecular Weight	247.01 g/mol
Synonyms	5-Nitro-2-bromonicotinic acid; 2-Bromo-5-nitropyridine-3-carboxylic acid; Nicotinic acid, 2-bromo-5-nitro-; 3-Pyridinecarboxylic acid, 2-bromo-5-nitro-; 2-Bromo-5-nitro-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Nitronicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.