Description

1-(5-Bromo-2-Fluoro-4-Methoxyphenyl)Ethanone is a high-purity, multi-functional aromatic ketone building block, essential for advanced organic synthesis. Its unique halogenated and methoxylated structure makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogenated aromatic core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and photoconductive polymers.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse client projects.
• Academic and R&D Laboratories: Utilized in methodological studies and for exploring new chemical reactions involving halogen-fluorine displacement or directed ortho-metalation.

Basic Information

Product Name	1-(5-Bromo-2-Fluoro-4-Methoxyphenyl)Ethanone
CAS No.	914221-54-8
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	5'-Bromo-2'-fluoro-4'-methoxyacetophenone; 1-Acetyl-5-bromo-2-fluoro-4-methoxybenzene; 2-Fluoro-5-bromo-4-methoxyacetophenone; 4'-Methoxy-5-bromo-2-fluoroacetophenone; 5-Bromo-2-fluoro-4-methoxyacetophenone; Ethanone, 1-(5-bromo-2-fluoro-4-methoxyphenyl)-; (5-Bromo-2-fluoro-4-methoxyphenyl)methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2-Fluoro-4-Methoxyphenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.