Description

5-(2-Chloronicotinoyl)-2-Furoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel drug candidates, offering a key building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides due to its bioactive nicotinoyl moiety.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical products.
• Bioconjugate Chemistry: The carboxylic acid group allows for conjugation to carriers, making it useful in prodrug and targeted delivery system development.

Basic Information

Item	Details
Product Name	5-(2-Chloronicotinoyl)-2-Furoic Acid
CAS No.	914203-45-5
Molecular Formula	C11H6ClNO4
Molecular Weight	251.62 g/mol
Synonyms	2-Furoic acid, 5-[(2-chloro-3-pyridinyl)carbonyl]-; 5-[(2-Chloropyridine-3-carbonyl)]furan-2-carboxylic acid; 5-(2-Chloronicotinoyl)furan-2-carboxylic acid; 2-Chloro-N-(5-carboxyfuran-2-yl)nicotinamide; 914203-45-5; 5-(2-Chloro-3-pyridinecarbonyl)-2-furancarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(2-Chloronicotinoyl)-2-Furoic Acid is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.