Description

4-(4-(2-Hydroxyethyl)Piperazine-1-Carbonyl)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique bifunctional structure, combining a boronic acid moiety with a piperazine-carbonyl linker, makes it an exceptionally versatile reagent for coupling reactions and pharmaceutical intermediate synthesis. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in Suzuki-Miyaura cross-coupling reactions to create biaryl structures common in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its boronic acid group enables efficient construction of complex molecular scaffolds.
• Material Science: Serves as a functional monomer or cross-linking agent in the production of advanced polymers, resins, and organic electronic materials.
• Bioconjugation Chemistry: Utilized for labeling and modifying biomolecules, proteins, and peptides due to its selective reactivity with diols and other functional groups.
• Chemical Synthesis Reagent: Acts as a versatile building block in organic synthesis for constructing complex molecules in medicinal chemistry and catalyst development.
• Diagnostic Agent Development: Employed in the research and creation of molecular probes and imaging agents for diagnostic applications.

Basic Information

Product Name	4-(4-(2-Hydroxyethyl)Piperazine-1-Carbonyl)Phenylboronic Acid
CAS No.	913835-44-6
Molecular Formula	C13H19BN2O4
Molecular Weight	278.12 g/mol
Synonyms	[4-(4-(2-Hydroxyethyl)piperazine-1-carbonyl)phenyl]boronic acid; 4-[4-(2-Hydroxyethyl)piperazine-1-carbonyl]benzeneboronic acid; 4-(4-(2-Hydroxyethyl)piperazine-1-carbonyl)benzeneboronic acid; 4-(4-(2-Hydroxyethyl)piperazin-1-yl)carbonylphenylboronic acid; B-[4-[[4-(2-Hydroxyethyl)-1-piperazinyl]carbonyl]phenyl]boronic acid; 913835-44-6; 4-(4-(2-Hydroxyethyl)piperazine-1-carbonyl)phenylboronic acid pinacol ester (common protected form)
EINECS	Contact for details

Quality Control

Our 4-(4-(2-Hydroxyethyl)Piperazine-1-Carbonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure compliance with high-purity research and industrial standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.