Description

4-(4-Methylpiperazine-1-Carbonyl)Phenylboronic Acid, HCl is a high-purity, advanced pharmaceutical intermediate and a key boronic acid derivative. This compound is specifically engineered for use in sophisticated organic synthesis, most notably in Suzuki-Miyaura cross-coupling reactions, which are fundamental for constructing complex molecules in drug discovery. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality reagents for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reagent: The boronic acid functional group enables efficient carbon-carbon bond formation, essential for constructing biaryl structures common in modern medicinal chemistry.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science & OLED Development: Serves as a precursor for creating organic electronic materials, including ligands for metal-organic frameworks (MOFs) and emissive layers in OLEDs.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Utilized in the design and synthesis of bifunctional molecules for targeted protein degradation.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic chemistry research.

Basic Information

Product Name	4-(4-Methylpiperazine-1-Carbonyl)Phenylboronic Acid, HCl
CAS No.	913835-43-5
Molecular Formula	C13H19BClN2O3
Molecular Weight	297.56 g/mol
Synonyms	[4-(4-Methyl-1-piperazinyl)carbonyl]benzeneboronic acid hydrochloride; 4-(4-Methylpiperazine-1-carbonyl)benzeneboronic acid hydrochloride; 4-(N-Methylpiperazine-1-carbonyl)phenylboronic acid HCl; 4-Carboxy(phenylboronic acid) 4-methylpiperazide hydrochloride; B-[4-[(4-Methyl-1-piperazinyl)carbonyl]phenyl]boronic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(4-Methylpiperazine-1-Carbonyl)Phenylboronic Acid, HCl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.