Description

4-(4-Fluoro-Benzenesulfonylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for critical synthesis pathways. This compound is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting specific enzyme inhibition. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors seeking reliable, high-quality building blocks for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those with piperidine and sulfonamide pharmacophores.
• Protease Inhibitor Research: Used in the development and screening of potential protease inhibitors for therapeutic applications.
• Kinase Inhibitor Synthesis: Serves as a precursor in the creation of targeted kinase inhibitors for oncology and inflammatory disease research.
• Chemical Biology & Probe Development: Employed in the design of chemical probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.
• Academic & Industrial R&D: A critical reagent for exploratory chemistry in both academic institutions and industrial R&D departments focused on heterocyclic chemistry.

Basic Information

Product Name	4-(4-Fluoro-Benzenesulfonylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	913634-49-8
Molecular Formula	C16H23FN2O4S
Molecular Weight	358.43 g/mol
Synonyms	1-Boc-4-[(4-fluorophenyl)sulfonylamino]piperidine; tert-Butyl 4-[(4-fluorophenyl)sulfonylamino]piperidine-1-carboxylate; 4-[(4-Fluorobenzenesulfonyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-[[(4-fluorophenyl)sulfonyl]amino]-1-piperidinecarboxylate; N-[(1-tert-Butoxycarbonyl-4-piperidinyl)]-4-fluorobenzenesulfonamide; 4-(4-Fluoro-benzenesulfonylamino)-piperidine-1-carboxylic acid tert-butyl ester; Boc-4-(4-fluorophenylsulfonamido)piperidine
EINECS	Contact for details

Quality Control

Our production of 4-(4-Fluoro-Benzenesulfonylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.