Description

1-(4-Fluorophenyl)-3-(Piperidin-4-Yl)Urea Hydrochloride is a high-purity organic salt compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or active pharmaceutical ingredient (API) building block, valued for its precise chemical structure and functionality. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly within the fields of central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new chemical entities (NCEs) for potential drug candidates.
• Biochemical Research: Used as a reference standard or tool compound in pharmacological studies to investigate biological pathways and receptor interactions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and method development.

Basic Information

Product Name	1-(4-Fluorophenyl)-3-(Piperidin-4-Yl)Urea Hydrochloride
CAS No.	913634-46-5
Molecular Formula	C12H16FN3O · HCl
Molecular Weight	273.74 g/mol (Free base: 237.28 g/mol)
Synonyms	1-(4-Fluorophenyl)-3-(4-piperidinyl)urea hydrochloride; 4-[(4-Fluorophenyl)carbamoylamino]piperidine hydrochloride; UNII-9J2Q0N8U8F; 1-(4-Fluorophenyl)-3-piperidin-4-yl-urea hydrochloride; N-(4-Fluorophenyl)-N'-(piperidin-4-yl)urea hydrochloride; 913634-46-5; 4-[3-(4-Fluorophenyl)ureido]piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)-3-(Piperidin-4-Yl)Urea Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccants or an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.