Description

tert-Butyl 4-[3-(4-Fluorophenyl)Ureido]Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative featuring a fluorinated phenylurea moiety. This compound serves as a critical pharmaceutical intermediate and research building block for the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and life science industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, kinase inhibition, and GPCR modulation.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in structure-activity relationship (SAR) studies and high-throughput screening.
• Peptidomimetic Synthesis: The piperidine core and urea linkage make it valuable for creating peptide-like molecules with enhanced metabolic stability.
• Agrochemical Development: Employed in research for developing new active ingredients for crop protection, leveraging the fluorophenyl group for bioactivity.
• Chemical Biology Probes: Useful for synthesizing labeled or tagged molecules to study biological pathways and protein interactions.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects requiring specific chiral or functionalized intermediates.

Basic Information

Product Name	tert-Butyl 4-[3-(4-Fluorophenyl)Ureido]Piperidine-1-Carboxylate
CAS No.	913634-45-4
Molecular Formula	C17H24FN3O3
Molecular Weight	337.39 g/mol
Synonyms	1-Boc-4-[(4-fluorophenyl)ureido]piperidine; tert-Butyl 4-[(4-fluorophenyl)carbamoylamino]piperidine-1-carboxylate; 4-[(4-Fluorophenyl)ureido]piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-[(4-fluorophenyl)ureido]piperidine; N-(4-Fluorophenyl)-N'-(1-Boc-4-piperidyl)urea; BOC-4-[(4-fluorophenyl)ureido]piperidine; 913634-45-4
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[3-(4-Fluorophenyl)Ureido]Piperidine-1-Carboxylate is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity suitable for research and development. Quality is assured through rigorous analytical testing, including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We adhere to a quality management system to meet the stringent requirements of our global pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.