Description

tert-Butyl 4-(4-Fluorobenzamido)Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical sector where precise chemical architecture is paramount. This compound is essential for research chemists and process development scientists working in medicinal chemistry, agrochemical discovery, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting a range of therapeutic areas, including central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to introduce the 4-fluorobenzamido-piperidine scaffold into novel compounds.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and pesticides requiring specific fluorine-containing motifs.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the scalable production of client-specific target molecules.
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) group allows for selective protection of the piperidine nitrogen, facilitating multi-step synthetic sequences.
• Chemical Library Development: A valuable reagent for creating diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	tert-Butyl 4-(4-Fluorobenzamido)Piperidine-1-Carboxylate
CAS No.	913634-42-1
Molecular Formula	C17H23FN2O3
Molecular Weight	322.38 g/mol
Synonyms	1-Boc-4-(4-fluorobenzamido)piperidine; 4-(4-Fluorobenzoylamino)-1-piperidinecarboxylic Acid tert-Butyl Ester; 1-(tert-Butoxycarbonyl)-4-[(4-fluorobenzoyl)amino]piperidine; N-(1-Boc-4-piperidinyl)-4-fluorobenzamide; 4-Fluoro-N-(1-(tert-butoxycarbonyl)piperidin-4-yl)benzamide; tert-Butyl 4-[(4-fluorobenzoyl)amino]piperidine-1-carboxylate; 913634-42-1; 4-(4-Fluorobenzamido)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Fluorobenzamido)Piperidine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch, detailing all relevant specifications to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.