Description

n-(1-(2,2-Difluoro-2-(4-(Trifluoromethyl)Phenyl)Ethyl)Piperidin-4-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure with multiple fluorine substitutions. This compound matters as a critical building block in modern medicinal chemistry, enabling the development of targeted therapeutics with enhanced metabolic stability and bioavailability. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of kinase inhibitors and other small-molecule drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Probe Development: Serves as a core structure for creating selective probes to study specific enzyme pathways and cellular signaling.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical-stage compounds.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in drug discovery and chemical biology.

Basic Information

Product Name	n-(1-(2,2-Difluoro-2-(4-(Trifluoromethyl)Phenyl)Ethyl)Piperidin-4-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
CAS No.	913574-42-2
Molecular Formula	C19H18F5N7
Molecular Weight	439.39 g/mol
Synonyms	4-Amino-1-(1-(2,2-difluoro-2-(4-(trifluoromethyl)phenyl)ethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidine; 913574-42-2; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, N-[1-[2,2-difluoro-2-[4-(trifluoromethyl)phenyl]ethyl]-4-piperidinyl]-; Kinase Inhibitor Intermediate; Difluorotrifluoromethyl Phenyl Pyrazolopyrimidine Amine
EINECS	Contact for details

Quality Control

Our n-(1-(2,2-Difluoro-2-(4-(Trifluoromethyl)Phenyl)Ethyl)Piperidin-4-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.