Description

tert-Butyl (1-(4-Fluorophenyl)But-3-En-1-Yl)Carbamate is a high-value, fluorinated chiral building block and pharmaceutical intermediate. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile handle for further chemical elaboration. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals, where its specific stereochemistry and functional groups are essential.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Organic Synthesis Building Block: Used in asymmetric synthesis, cross-coupling reactions, and other advanced transformations to introduce a fluorinated phenyl and a protected amine moiety.
• Agrochemical Research: Serves as a precursor in the development of new generation pesticides and herbicides that require specific fluorinated aromatic structures.
• Material Science: Potential use in the synthesis of specialty polymers and advanced materials where fluorinated aromatic compounds impart unique properties.
• Academic & Contract Research: Employed in university laboratories and CROs (Contract Research Organizations) for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	tert-Butyl (1-(4-Fluorophenyl)But-3-En-1-Yl)Carbamate
CAS No.	913563-71-0
Molecular Formula	C₁₅H₂₀FNO₂
Molecular Weight	265.33 g/mol
Synonyms	Boc-4-Fluorophenylbut-3-enylamine; 1-Boc-amino-1-(4-fluorophenyl)-3-butene; tert-Butyl N-[1-(4-fluorophenyl)but-3-en-1-yl]carbamate; 1-(4-Fluorophenyl)-3-buten-1-amine, N-BOC derivative; N-Boc-1-(4-fluorophenyl)-3-buten-1-amine; (1-(4-Fluorophenyl)but-3-en-1-yl)carbamic acid tert-butyl ester; BOC-Protected 1-(4-Fluorophenyl)-3-buten-1-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl (1-(4-Fluorophenyl)But-3-En-1-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, NMR, and MS for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere such as nitrogen to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.