Description

3-(6-(Pyrrolidin-1-Yl)-[1,2,4]Triazolo[4,3-B]Pyridazin-3-Yl)Propanoic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique triazolopyridazine core. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) and metabolic disorders. Pharmaceutical R&D teams and fine chemical manufacturers need this material for developing next-generation therapeutics, where its precise structure enables the exploration of new biological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for CNS-targeting therapies.
• Biochemical Research: Used as a reference standard or probe molecule in pharmacological and enzymatic studies.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale API production.
• Academic Research: Utilized in university and institutional labs for investigating heterocyclic chemistry and new synthetic methodologies.

Basic Information

Product Name	3-(6-(Pyrrolidin-1-Yl)-[1,2,4]Triazolo[4,3-B]Pyridazin-3-Yl)Propanoic Acid
CAS No.	913527-48-7
Molecular Formula	C14H17N5O2
Molecular Weight	287.32 g/mol
Synonyms	3-[6-(Pyrrolidin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]propanoic acid; 3-(6-(1-Pyrrolidinyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanoic Acid; 913527-48-7; 3-(6-(Pyrrolidin-1-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl)propanoic acid; Propanoic acid, 3-[6-(1-pyrrolidinyl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]-; Triazolopyridazine propanoic acid derivative
EINECS	Contact for details

Quality Control

Our 3-(6-(Pyrrolidin-1-Yl)-[1,2,4]Triazolo[4,3-B]Pyridazin-3-Yl)Propanoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 standards, and we support development projects requiring ICH stability guidelines and regulatory starting material documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.