Description

(S)-2-tert-Butoxycarbonylamino-5-Oxo-Hexanoic Acid Ethyl Ester is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical intermediate in the production of complex pharmaceutical actives and bioactive peptides, offering precise stereochemical control. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, enzyme modulators, and other small-molecule drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate specific amino acid sequences with a Boc-protected α-amino group.
• Chemical Biology Research: Employed in the design and construction of peptide mimetics, molecular probes, and labeled compounds for biochemical studies.
• Asymmetric Synthesis: A valuable starting material for constructing complex natural products and chiral compounds requiring the (S)-2-amino-5-oxo-hexanoic acid scaffold.
• API Development: Intermediate in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) targeting metabolic and neurological disorders.

Basic Information

Product Name	(S)-2-tert-Butoxycarbonylamino-5-Oxo-Hexanoic Acid Ethyl Ester
CAS No.	913251-58-8
Molecular Formula	C13H23NO6
Molecular Weight	289.33 g/mol
Synonyms	Boc-L-5-Oxo-norleucine Ethyl Ester; (S)-Ethyl 2-((tert-butoxycarbonyl)amino)-5-oxohexanoate; Boc-5-Oxo-L-norleucine-OEt; L-5-Oxo-norleucine, N-Boc-, ethyl ester; Ethyl (2S)-2-[(tert-butoxycarbonyl)amino]-5-oxohexanoate; (S)-2-(Boc-amino)-5-oxohexanoic acid ethyl ester; Boc-L-5-Oxo-Nle-OEt
EINECS	Contact for details

Quality Control

Our (S)-2-tert-Butoxycarbonylamino-5-Oxo-Hexanoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent specifications for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.