Description

2,2,2-Trifluoro-n-[2-(4-Fluorophenyl)-Ethyl]Acetamide is a specialized fluorinated acetamide derivative, a high-value building block in advanced organic synthesis. Its molecular structure, featuring both a trifluoroacetyl group and a fluorinated aromatic side chain, makes it a critical intermediate for developing novel compounds with enhanced biological activity and physicochemical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating new active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms can improve metabolic stability, lipophilicity, and overall efficacy.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced materials with specific thermal, chemical, or surface properties.
• Ligand & Catalyst Development: Employed in organometallic chemistry for designing novel ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and the effects of fluorination on molecular behavior in academic and industrial R&D settings.
• Diagnostic Agent Synthesis: Potential intermediate in the production of contrast agents or radiolabeled compounds for medical imaging (e.g., PET tracers).

Basic Information

Product Name	2,2,2-Trifluoro-n-[2-(4-Fluorophenyl)-Ethyl]Acetamide
CAS No.	912846-63-0
Molecular Formula	C10H9F4NO
Molecular Weight	235.18 g/mol
Synonyms	N-[2-(4-Fluorophenyl)ethyl]-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-[2-(4-fluorophenyl)ethyl]acetamide; 2,2,2-Trifluoroacetamide, N-[2-(4-fluorophenyl)ethyl]-; 4-Fluorophenethyltrifluoroacetamide; N-(2-(4-Fluorophenyl)ethyl)trifluoroacetamide; 2,2,2-Trifluoro-N-(2-(4-fluorophenyl)ethyl)acetamide; 912846-63-0; FPEA-TFA (common abbreviation)
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-[2-(4-Fluorophenyl)-Ethyl]Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.