Description

7-(4-Methoxyphenyl)-7,8-Dihydro-8-Oxo-1,2,4-Triazolo[4,3-A]Pyrazine-3-Propanoic Acid CAS NO 912791-23-2 is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused triazolopyrazine core. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought after by research organizations, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

This specialized intermediate serves critical functions in sophisticated chemical synthesis pipelines.

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Drug Discovery & Medicinal Chemistry: Used as a scaffold for constructing compound libraries via parallel synthesis to explore structure-activity relationships (SAR).
• Process Chemistry & Route Scouting: Serves as a benchmark material for developing and optimizing scalable, cost-effective synthetic routes for new chemical entities (NCEs).
• Reference Standard: Employed as an analytical standard for quality control and method validation during API development and regulatory submissions.
• Biochemical Research: Potential use as a tool compound or probe in enzymatic or receptor-binding assays due to its heterocyclic structure.

Basic Information

Product Name	7-(4-Methoxyphenyl)-7,8-Dihydro-8-Oxo-1,2,4-Triazolo[4,3-A]Pyrazine-3-Propanoic Acid
CAS No.	912791-23-2
Molecular Formula	C₁₇H₁₆N₄O₄
Molecular Weight	340.34 g/mol
Synonyms	7-(4-Methoxyphenyl)-7,8-dihydro-8-oxo-[1,2,4]triazolo[4,3-a]pyrazine-3-propanoic acid; 1,2,4-Triazolo[4,3-a]pyrazine-3-propanoic acid, 7-(4-methoxyphenyl)-7,8-dihydro-8-oxo-; 912791-23-2; 7-(p-Methoxyphenyl)-7,8-dihydro-8-oxo-1,2,4-triazolo[4,3-a]pyrazine-3-propionic acid; Triazolopyrazine propanoic acid derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and reliability for critical R&D and scale-up work. Each lot is subjected to comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profile is provided with every shipment, supporting your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.