Description

(1-Cyano-Cyclopentyl)-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its cyano and protected carbamate functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Protease Inhibitor Research: Serves as a precursor in the development of protease inhibitors, which are crucial for antiviral and anticancer therapies.
• Peptidomimetic Chemistry: Used to introduce constrained cyclopentyl scaffolds and protected amine functionalities into peptidomimetic compounds, enhancing their metabolic stability and bioavailability.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening in early-stage drug discovery.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke intermediates under cGMP conditions.

Basic Information

Product Name	(1-Cyano-Cyclopentyl)-Carbamic Acid tert-Butyl Ester
CAS No.	912770-99-1
Molecular Formula	C11H18N2O2
Molecular Weight	210.27 g/mol
Synonyms	tert-Butyl (1-cyanocyclopentyl)carbamate; 1-Cyano-1-((tert-butoxycarbonyl)amino)cyclopentane; N-Boc-1-amino-1-cyanocyclopentane; Boc-1-Amino-1-cyanocyclopentane; 1-((tert-Butoxycarbonyl)amino)cyclopentanecarbonitrile; (1-Cyano-cyclopentyl)-carbamic acid tert-butyl ester; 912770-99-1; BOC-ACPCN
EINECS	Contact for details

Quality Control

Our (1-Cyano-Cyclopentyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.