Description

6-(4-Fluorophenyl)Imidazo[2,1-B][1,3]Thiazole-3-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique fused imidazothiazole core with a fluorinated aromatic substituent makes it a valuable scaffold for developing novel bioactive compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, anti-infective agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the imidazothiazole moiety.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or linker in the design of chemical probes and activity-based protein profiling (ABPP) reagents.
• Material Science: Investigated as a monomer or functional additive for creating specialty polymers with specific electronic or optical properties.
• Academic & Contract Research: Serves as a versatile starting material for methodological studies and novel heterocycle construction in university and CRO laboratories.

Basic Information

Product Name	6-(4-Fluorophenyl)Imidazo[2,1-B][1,3]Thiazole-3-Carboxylic Acid
CAS No.	912770-37-7
Molecular Formula	C₁₂H₇FN₂O₂S
Molecular Weight	262.26 g/mol
Synonyms	6-(4-Fluorophenyl)imidazo[2,1-b][1,3]thiazole-3-carboxylic acid; 6-(4-Fluorophenyl)-3-carboxyimidazo[2,1-b]thiazole; Imidazo[2,1-b][1,3]thiazole-3-carboxylic acid, 6-(4-fluorophenyl)-; 912770-37-7; 6-(p-Fluorophenyl)imidazo[2,1-b]thiazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 6-(4-Fluorophenyl)Imidazo[2,1-B][1,3]Thiazole-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.