Description

6-(2-Chloro-Phenyl)-Imidazo[2,1-B]Thiazole-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the imidazothiazole class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and anti-inflammatory agents.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides with specific modes of action.
• Chemical Biology & Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and high-throughput screening to identify new bioactive molecules.
• Organic Synthesis: Employed as a versatile scaffold for constructing complex heterocyclic systems in academic and industrial R&D laboratories.
• Reference Standard: Supplied as a certified reference material (CRM) for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Item	Detail
Product Name	6-(2-Chloro-Phenyl)-Imidazo[2,1-B]Thiazole-3-Carboxylic Acid
CAS No.	912770-05-9
Molecular Formula	C12H7ClN2O2S
Molecular Weight	278.71 g/mol
Synonyms	6-(2-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-3-carboxylic acid; 2-Chloro-6-imidazo[2,1-b]thiazole-3-carboxylic acid phenyl derivative; Imidazo[2,1-b]thiazole-3-carboxylic acid, 6-(2-chlorophenyl)-; 912770-05-9; 6-(o-Chlorophenyl)imidazo[2,1-b]thiazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 6-(2-Chloro-Phenyl)-Imidazo[2,1-B]Thiazole-3-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support audits for cGMP compliance where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.