Description

tert-Butyl 4-(2-Methylbenzoyl)Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable building blocks for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its piperidine core structure.
• Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex heterocyclic compounds and functionalized piperidines.
• Academic & R&D: Employed in university and corporate research laboratories for method development and exploratory chemistry projects.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.
• Ligand & Catalyst Development: Potential use in creating novel ligands for catalysis or as a structural component in catalyst design.

Basic Information

Product Name	tert-Butyl 4-(2-Methylbenzoyl)Piperidine-1-Carboxylate
CAS No.	912769-10-9
Molecular Formula	C18H25NO3
Molecular Weight	303.40 g/mol
Synonyms	1-Boc-4-(2-methylbenzoyl)piperidine; 1-(tert-Butoxycarbonyl)-4-(2-methylbenzoyl)piperidine; 4-(2-Methylbenzoyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(o-toluoyl)piperidine-1-carboxylate; 912769-10-9; 4-(2-Methylbenzoyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-Piperidinecarboxylic acid, 4-(2-methylbenzoyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Methylbenzoyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.