Description

tert-Butyl 4-(4-Methylbenzoyl)Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile synthetic intermediate, enabling the construction of complex molecular architectures with high precision. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its piperidine scaffold for bioactivity.
• Chemical Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized fine chemicals and APIs (Active Pharmaceutical Ingredients).
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and the exploration of new chemical reactions.

Basic Information

Product Name	tert-Butyl 4-(4-Methylbenzoyl)Piperidine-1-Carboxylate
CAS No.	912768-78-6
Molecular Formula	C18H25NO3
Molecular Weight	303.40 g/mol
Synonyms	1-Boc-4-(4-methylbenzoyl)piperidine; 4-(4-Methylbenzoyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(p-toluoyl)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(4-methylbenzoyl)piperidine; N-Boc-4-(4-methylbenzoyl)piperidine; 912768-78-6; 4-(4-Methylbenzoyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Methylbenzoyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.