Description

1H-Imidazole, 5-(2-Fluorophenyl)- is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals and agrochemicals, where the imidazole core and fluorine substituent impart desirable biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting kinases, GPCRs, and other enzymes where the imidazole scaffold is prevalent.
• Agrochemical Research: Used in the development of new fungicides, herbicides, and insecticides, leveraging the bioactivity of the fluorinated imidazole structure.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic electronic materials and advanced polymers where fluorinated aromatic systems are valuable.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	1H-Imidazole, 5-(2-Fluorophenyl)-
CAS No.	912763-52-1
Molecular Formula	C9H7FN2
Molecular Weight	162.17 g/mol
Synonyms	5-(2-Fluorophenyl)-1H-imidazole; 2-Fluorophenylimidazole; 5-(2-Fluorophenyl)imidazole; 1H-Imidazole, 5-(2-fluorophenyl)-; 2-Fluoro-5-imidazolylbenzene; (2-Fluorophenyl)-1H-imidazole; 5-(o-Fluorophenyl)imidazole
EINECS	Contact for details

Quality Control

Our 1H-Imidazole, 5-(2-Fluorophenyl)- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.