Description

[2-Amino-2-(3,4-Dimethoxy-Phenyl)-Ethyl]-Carbamic Acid tert-Butyl Ester is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive amine handle for the controlled construction of complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Peptidomimetic Scaffold: Used to construct non-peptide structures that mimic the biological activity of peptides, improving metabolic stability and bioavailability.
• Chiral Building Block: Employed in asymmetric synthesis to introduce stereogenic centers into target molecules, crucial for producing enantiomerically pure compounds.
• Chemical Biology Probe Development: Incorporated into molecular probes for studying enzyme function, receptor binding, and cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.
• Academic & Industrial R&D: Utilized in research laboratories for method development and exploring new synthetic routes to complex heterocycles and natural product analogs.

Basic Information

Product Name	[2-Amino-2-(3,4-Dimethoxy-Phenyl)-Ethyl]-Carbamic Acid tert-Butyl Ester
CAS No.	912762-97-1
Molecular Formula	C15H24N2O4
Molecular Weight	296.36 g/mol
Synonyms	N-Boc-2-Amino-2-(3,4-dimethoxyphenyl)ethylamine; tert-Butyl N-[2-amino-2-(3,4-dimethoxyphenyl)ethyl]carbamate; 2-(3,4-Dimethoxyphenyl)-2-[(tert-butoxycarbonyl)amino]ethanamine; Boc-DAPE; Boc-3,4-Dimethoxy-Phe-NH2; (2-Amino-2-(3,4-dimethoxyphenyl)ethyl)carbamic acid tert-butyl ester; N-(tert-Butoxycarbonyl)-2-(3,4-dimethoxyphenyl)-1,2-ethanediamine
EINECS	Contact for details

Quality Control

Our [2-Amino-2-(3,4-Dimethoxy-Phenyl)-Ethyl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and mass spectrometry. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting development from research scale through to pre-clinical and clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.