Description

[2-Amino-2-(4-Methoxy-Phenyl)-Ethyl]-Carbamic Acid tert-Butyl Ester Hydrochloride is a high-purity, protected amino acid derivative and a key chiral building block in advanced organic synthesis. Its primary value lies in providing a versatile, enantiomerically pure intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for API synthesis and process scale-up.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Peptidomimetics Synthesis: Used in the construction of peptidomimetic scaffolds and non-natural amino acid residues for drug discovery programs targeting protease inhibition.
• Asymmetric Synthesis: Serves as a versatile building block in asymmetric synthesis for introducing the 2-amino-2-aryl-ethylamine moiety with high enantiomeric purity.
• Agrochemical Research: Employed in the development of advanced chiral herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: A precursor for creating chiral ligands and organocatalysts used in enantioselective transformations.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals.

Basic Information

Item	Detail
Product Name	[2-Amino-2-(4-Methoxy-Phenyl)-Ethyl]-Carbamic Acid tert-Butyl Ester Hydrochloride
CAS No.	912762-82-4
Molecular Formula	C14H22N2O3 • HCl
Molecular Weight	302.80 g/mol
Synonyms	N-Boc-1-(4-Methoxyphenyl)ethylenediamine Hydrochloride; tert-Butyl N-[2-Amino-2-(4-methoxyphenyl)ethyl]carbamate Hydrochloride; (R/S)-N-Boc-1-(4-Methoxyphenyl)ethylenediamine HCl; 2-[(tert-Butoxycarbonyl)amino]-2-(4-methoxyphenyl)ethanamine Hydrochloride; Boc-4-MeO-Phe-NH2 • HCl; BOC-1-(4-Methoxyphenyl)ethylenediamine hydrochloride; (2-Amino-2-(4-methoxyphenyl)ethyl)carbamic acid 1,1-dimethylethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our [2-Amino-2-(4-Methoxy-Phenyl)-Ethyl]-Carbamic Acid tert-Butyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles are provided with every shipment. We support compliance with ICH guidelines and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.