Description

(2-Hydroxyimino-2-Phenyl-Ethyl)-Carbamic Acid tert-Butyl Ester is a specialized chemical intermediate featuring a protected carbamate group and an oxime functional group. This unique structure makes it a valuable building block in organic synthesis, particularly for the construction of complex molecules in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of target drug molecules, especially those requiring oxime or protected amine functionalities.
• Peptidomimetic Research: Serves as a building block for creating peptide analogs and mimetics in medicinal chemistry programs.
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) group is used for the temporary protection of amines during complex synthetic sequences.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides or insecticides where its molecular scaffold is incorporated.
• Chemical Biology Probes: Used in the development of molecular probes and tools for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis organizations (CSOs) and CDMOs producing client-specific compounds.

Basic Information

Product Name	(2-Hydroxyimino-2-Phenyl-Ethyl)-Carbamic Acid tert-Butyl Ester
CAS No.	912762-45-9
Molecular Formula	C₁₃H₁₈N₂O₃
Molecular Weight	250.29 g/mol
Synonyms	tert-Butyl N-(2-hydroxyimino-2-phenylethyl)carbamate; N-Boc-2-(hydroxyimino)-2-phenylethylamine; 2-(Hydroxyimino)-2-phenylethylcarbamic Acid tert-Butyl Ester; Boc-Aminoacetophenone Oxime; (2-Oximino-2-phenylethyl)carbamic Acid tert-Butyl Ester; N-(tert-Butoxycarbonyl)-2-(hydroxyimino)-2-phenylethylamine; 912762-45-9
EINECS	Contact for details

Quality Control

Every batch of (2-Hydroxyimino-2-Phenyl-Ethyl)-Carbamic Acid tert-Butyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.