Description

[2-(3,4-Dimethoxy-Phenyl)-2-Oxo-Ethyl]-Carbamic Acid tert-Butyl Ester is a specialized organic compound featuring a protected carbamate group and a dimethoxyphenyl ketone moiety. This molecular architecture makes it a valuable key intermediate in advanced organic synthesis, particularly for constructing complex pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers requiring high-purity building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or cardiovascular pathways.
• Peptidomimetic Research: Used in the development of peptide analogs and protease inhibitors due to its protected amine functionality.
• Chemical Biology Probes: Serves as a precursor for creating labeled compounds or molecular probes for studying enzyme mechanisms and binding interactions.
• Agrochemical Synthesis: An intermediate in the development of advanced herbicides or plant growth regulators leveraging its aromatic ether and ketone groups.
• Material Science Precursor: Potential use in synthesizing specialty monomers for advanced polymers with specific optical or electronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	[2-(3,4-Dimethoxy-Phenyl)-2-Oxo-Ethyl]-Carbamic Acid tert-Butyl Ester
CAS No.	912762-37-9
Molecular Formula	C15H21NO5
Molecular Weight	295.33 g/mol
Synonyms	N-Boc-2-amino-1-(3,4-dimethoxyphenyl)ethanone; tert-Butyl N-[2-(3,4-dimethoxyphenyl)-2-oxoethyl]carbamate; 2-[(tert-Butoxycarbonyl)amino]-1-(3,4-dimethoxyphenyl)ethanone; Boc-Amino(3,4-dimethoxyphenyl)ketone; (3,4-Dimethoxyphenyl)(N-Boc-amino)methyl ketone; N-(tert-Butoxycarbonyl)-2-amino-3',4'-dimethoxyacetophenone; 2-Amino-1-(3,4-dimethoxyphenyl)ethanone tert-butyl carbamate; Boc-3,4-Dimethoxy-ω-aminoacetophenone
EINECS	Contact for details

Quality Control

Our production of [2-(3,4-Dimethoxy-Phenyl)-2-Oxo-Ethyl]-Carbamic Acid tert-Butyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting purity, impurity profiles, and physical data. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.