Description

(2R)-n-[[5-[3-(2,5-Difluorophenyl)-2-(1,3-Dihydro-2H-Benzimidazol-2-Ylidene)-1,3-Dioxopropyl]-2-Fluorophenyl]Sulfonyl]-2-Hydroxypropanimidamide is a sophisticated, high-purity organic compound featuring a benzimidazole core and a sulfonamide group, designed for advanced research and development. This molecule is of significant interest for its potential as a key pharmaceutical intermediate or a biological probe in drug discovery programs. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for synthesizing novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential new chemical entities (NCEs) for drug discovery.
• Biochemical Research: Used as a tool compound or a probe to study specific biological pathways and enzyme interactions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Process Chemistry: Utilized in the development and scale-up of synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in analytical laboratories.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals.

Basic Information

Product Name	(2R)-n-[[5-[3-(2,5-Difluorophenyl)-2-(1,3-Dihydro-2H-Benzimidazol-2-Ylidene)-1,3-Dioxopropyl]-2-Fluorophenyl]Sulfonyl]-2-Hydroxypropanimidamide
CAS No.	912587-25-8
Molecular Formula	C25H19F3N4O5S
Molecular Weight	544.50 g/mol
Synonyms	(2R)-N-[[5-[3-(2,5-Difluorophenyl)-2-(1,3-dihydro-2H-benzimidazol-2-ylidene)-1,3-dioxopropyl]-2-fluorophenyl]sulfonyl]-2-hydroxypropanimidamide; 912587-25-8; Propanimidamide, N-[[5-[3-(2,5-difluorophenyl)-2-(1,3-dihydro-2H-benzimidazol-2-ylidene)-1,3-dioxopropyl]-2-fluorophenyl]sulfonyl]-2-hydroxy-, (2R)-; Benzimidazole sulfonamide derivative; (2R)-2-Hydroxy-N-({2-fluoro-5-[3-oxo-3-(2,5-difluorophenyl)-1-(1,3-dihydro-2H-benzimidazol-2-ylidene)propyl]phenyl}sulfonyl)propanimidamide
EINECS	Contact for details

Quality Control

Our (2R)-n-[[5-[3-(2,5-Difluorophenyl)-2-(1,3-Dihydro-2H-Benzimidazol-2-Ylidene)-1,3-Dioxopropyl]-2-Fluorophenyl]Sulfonyl]-2-Hydroxypropanimidamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), chromatographic data, and spectroscopic identification is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere at -20°C to maximize stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.