Description

2-Amino-5-Fluoro-3-Nitrobenzonitrile is a high-purity, multi-functional aromatic nitrile building block. This compound is valued for its unique molecular scaffold, which incorporates reactive amino, fluoro, and nitro groups, enabling diverse synthetic transformations. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Research: Serves as a building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the production of advanced colorants and fluorescent markers due to its conjugated nitro and amino substituents.
• Chemical Biology Probe: Useful for designing molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	2-Amino-5-Fluoro-3-Nitrobenzonitrile
CAS No.	912444-99-6
Molecular Formula	C7H4FN3O2
Molecular Weight	181.13 g/mol
Synonyms	5-Fluoro-2-amino-3-nitrobenzonitrile; 3-Nitro-2-amino-5-fluorobenzonitrile; 2-Amino-5-fluoro-3-nitrobenzenecarbonitrile; Benzonitrile, 2-amino-5-fluoro-3-nitro-; 912444-99-6; 5-Fluoro-3-nitroanthranilonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Fluoro-3-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to prevent degradation and absorption of moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.