Description

(R)-Benzyl 2-(7-Carbamoyl-1H-Benzo[D]Imidazol-2-Yl)-2-Methylpyrrolidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly in drug discovery and development. It is primarily needed by research institutions, pharmaceutical companies, and CDMOs (Contract Development and Manufacturing Organizations) focused on creating novel therapeutics, especially in areas like oncology and targeted enzyme inhibition.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Protease Inhibitor Development: Serves as a core scaffold for designing inhibitors targeting specific enzymatic pathways.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological mechanisms and target validation.
• Custom Synthesis: Employed by contract research organizations (CROs) for bespoke chemical synthesis projects.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and methodological studies.

Basic Information

Item	Details
Product Name	(R)-Benzyl 2-(7-Carbamoyl-1H-Benzo[D]Imidazol-2-Yl)-2-Methylpyrrolidine-1-Carboxylate
CAS No.	912444-73-6
Molecular Formula	C21H22N4O3
Molecular Weight	378.43 g/mol
Synonyms	(R)-Benzyl 2-(7-Carbamoyl-1H-benzo[d]imidazol-2-yl)-2-methylpyrrolidine-1-carboxylate; 1-[(Benzyloxy)carbonyl]-2-methyl-2-(7-carbamoyl-1H-benzimidazol-2-yl)pyrrolidine, (2R)-; 912444-73-6; (R)-1-CBZ-2-Methyl-2-(7-carbamoyl-1H-benzoimidazol-2-yl)pyrrolidine; (R)-1-N-CBZ-2-Methyl-2-(7-carbamoyl-1H-benzoimidazol-2-yl)pyrrolidine; (2R)-1-[(Benzyloxy)carbonyl]-2-methyl-2-(7-carbamoyl-1H-1,3-benzodiazol-2-yl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-Benzyl 2-(7-Carbamoyl-1H-Benzo[D]Imidazol-2-Yl)-2-Methylpyrrolidine-1-Carboxylate is manufactured under strict quality systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot to guarantee identity, potency, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.