Description

Ethanone, 1-(2-Amino-1-cyclopenten-1-yl)-2,2,2-trifluoro- is a specialized trifluoromethyl ketone derivative featuring a cyclopentenyl amine moiety, making it a valuable chiral building block for advanced synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms and a constrained cyclic structure can dramatically enhance biological activity and metabolic stability. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in protease inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves lipophilicity and target binding.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Research: An important substrate for studying fluorination reactions and the effects of fluorine substitution on chemical reactivity and physical properties.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Material Science Precursor: Potential use in the synthesis of monomers for specialty polymers with unique thermal and chemical resistance profiles.

Basic Information

Product Name	Ethanone, 1-(2-Amino-1-cyclopenten-1-yl)-2,2,2-trifluoro-
CAS No.	912335-17-2
Molecular Formula	C7H8F3NO
Molecular Weight	179.14 g/mol
Synonyms	1-(2-Amino-1-cyclopenten-1-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(2-amino-1-cyclopenten-1-yl)ethanone; 2-Amino-1-(2,2,2-trifluoroacetyl)cyclopentene; 1-(2-Amino-1-cyclopentenyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(2-aminocyclopent-1-en-1-yl)ethanone; Trifluoroacetyl cyclopentenyl amine; α-(Aminocyclopentenyl)trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-(2-Amino-1-cyclopenten-1-yl)-2,2,2-trifluoro- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent decomposition. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.